必威bet体育|官网首页

必威bet体育|官网首页

http://www.hsddcex.com

菜单导航
近日,世卫组织专家谭德塞在专业杂志《家庭医药Home Medicine》发表题为ldquo;灵芝七种主要成份及抗癌作用研究rdquo;的

世卫专家谭德赛发表中文论文提及香港华人堂国际集团产品

作者: 必威体育 发布时间: 2020年06月29日 23:06:24

近日,世卫组织专家谭德塞在专业杂志《家庭医药Home Medicine》发表题为“灵芝七种主要成份及抗癌作用研究”的论文。据检索,这是谭德塞博士首次用中文发表专业研究成果。

Recently, Dr. Tan published a paper entitled "Research on seven main ingredients of Ganoderma lucidum and its anticancer effect" in the professional journal <Home Medicine>. According to the search, this is the first time Dr. Tan has published professional research results in Chinese.

世卫专家谭德赛发表中文论文提及香港华人堂国际集团产品

图1《家庭医药Home Medicine》2020年第五期

谭德塞博士发现,癌症患者在常规治疗同时服用灵芝提取物(GLE),生活质量得到改善,生存期得以延长。灵芝提取物(GLE)主要含有与子实体相似的三萜和多糖,这是灵芝GLE抗癌活性的最主要化学成分。

Dr. Tan found that the quality of life and survival time of cancer patients were improved by taking Ganoderma lucidum extract (GLE) at the same time of conventional treatment. The extract of Ganoderma lucidum (GLE) mainly contains triterpenoids and polysaccharides similar to the fruiting body, which is the main chemical component of the anti-cancer activity of GLE.

谭德塞博士研究的目的是阐明GLE的化学成分生物学活性的影响,并确定其作为单一物质在各种肿瘤细胞模型中的疗效。谭德塞博士对灵芝GLE七种最丰富的成份进行结构解析,证明这些化合物(包括三萜和甾醇)在各种癌症模型中的体外疗效。

The aim of Dr.Tan's research is to elucidate the influence of the chemical components of GLE on its biological activity and to determine its efficacy as a single substance in various tumor cell models. Dr. Tan Desai carried out structural analysis on the seven most abundant chemical components, proving the in vitro efficacy of these compounds, including triterpenoids and sterols, in various cancer models.

世卫专家谭德赛发表中文论文提及香港华人堂国际集团产品

图2 实验采用华人堂国际集团出品的灵芝孢子油胶囊(500mg)作为样品

为了验证其研究成果,谭德塞博士采用华人堂国际集团出品的灵芝孢子油胶囊(500mg)作为实验样品,通过细胞培养、细胞活力测定、细胞周期分析、细胞死亡检测和迁移和入侵分析等实验步骤。

In order to verify his research results, Dr. Tan  took Ganoderma lucidum spore oil capsule (500mg) produced by Hong Kong CHNTown International Group as the experimental sample, through the experimental steps of cell culture, cell viability determination, cell cycle analysis, cell death detection, migration and invasion analysis.

谭德塞博士的实验结果阐述了灵芝中含量最丰富的七种化学成份结构及其在癌症模型中的作用。实验结果表明,分离出的GLE化合物在多个癌细胞系中显示出生物活性,具有不同程度的效力。EP作为GLE的单组分,是最具生物活性的癌细胞抗侵袭化合物,EC50值在低浓度范围内,在正常细胞中具有丰富的治疗指标。GA-01和EP不通过抑制蛋白质合成而对增殖起作用,细胞死亡是由caspase激活通过癌症依赖机制(如AKT-pro生存途径)的调节介导的。谭德塞博士的实验数据表明,GA-01、麦角固醇、5,6-脱氢麦角固醇和EP在乳腺癌细胞模型中诱导了ROS, EP调节AKT,随后减少参与癌细胞生存、增殖和进展的蛋白质。

The results of Dr. Tan's experiment described the structure of the seven most abundant chemical components in Ganoderma lucidum and their role in cancer models. The results showed that the separated GLE compounds showed biological activity in multiple cancer cell lines and had different degrees of potency. EP, as a single component of GLE, is the most biologically active anti-invasive compound of cancer cells. EC50 value is in the low concentration range, and has rich therapeutic indicators in normal cells. Ga-01 and EP do not inhibit protein synthesis and play a role in proliferation. Cell death is mediated by caspase activation through cancer dependent mechanisms such as Akt Pro survival pathway. According to Dr. Tan 's experimental data, ga-01, ergosterol, 5,6-dehydrolergosterol and EP induced ROS and EP regulated Akt in breast cancer cell model, and then reduced the proteins involved in the survival, proliferation and progression of cancer cells.

世卫专家谭德赛发表中文论文提及香港华人堂国际集团产品

图3 谭德赛博士论文节选

公开资料显示,华人堂国际集团成立于2005年,总部香港,致力于草本药用植物的科学化体系化研究,用科技的手段探索草本的秘密。华人堂国际集团是重症“助愈”理念的开创者,旗下拥有“华人堂”和“助愈”两大品牌。华人堂认为因科技发展水平所限,诸多重症无法完全治愈,但是人类可以利用安全低廉的草本成分,激发人体自身免疫力,与疾病共存,同样获得良好的效果。

welcome